Abstract

This manuscript summarizes the break-out session held on anti-retroviral drugs and vaccines at the Koala Conservation Workshop: The koala and its retroviruses: implications for sustainability and survival held at San Diego Zoo, April 17–18, 2013. Discussants considered the utility of natural retroviral systems as models for treatment and prevention of koala retrovirus (KoRV) infection, in particular, feline leukemia virus infection of the cat and AIDS virus infections of humans and non-human primates. Key lessons learned from those model systems may be applicable to the development of anti-retroviral drugs for treatment of KoRV infection or vaccines to prevent it. Aspects of the experience with model systems that are most likely to be translatable to KoRV infection include the identification of optimal drug targets, parameters for drug delivery, components of an effective vaccine, and approaches to measure protection.

 
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Bibliographic Data

Short Form
Levy and Lifson, 2014. Tech. Rep. Aust. Mus., Online 24: 93–95
Author
Laura S. Levy; Jeffrey D. Lifson
Year
2014
Title
Anti-retroviral drugs and vaccines
Serial Title
Technical Reports of the Australian Museum, Online
Volume
24
Start Page
93
End Page
95
DOI
10.3853/j.1835-4211.24.2014.1625
Language
English
Date Published
30 May 2014
Cover Date
30 May 2014
ISSN
1835-4211 (online)
Publisher
The Australian Museum
Place Published
Sydney, Australia
Subjects
RETROVIRUS; ANIMAL DISEASE; VIROLOGY; MAMMALIA: MARSUPIALIA
Digitized
30 May 2014
Available Online
30 May 2014
Reference Number
1625
EndNote
/Uploads/Journals/30998/1625.enw
Title Page
/Uploads/Journals/30998/1625.pdf
File size: 160kB
Complete Work
/Uploads/Journals/30998/1625_complete.pdf
File size: 311kB